ATN-161 (trifluoroacetate salt)-其他肽-ELISA_抗体_蛋白_核苷酸_试剂盒-深圳九游会j9网站首页有限公司

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ATN-161 (trifluoroacetate salt)

品牌：Cayman

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说明书

折扣/货期

货号：34056-1 mg	规格：1 mg	目录价：￥448
货号：34056-10 mg	规格：10 mg	目录价：￥2786
货号：34056-25 mg	规格：25 mg	目录价：￥4788
货号：34056-5 mg	规格：5 mg	目录价：￥1624

产品详情

产品名称:

ATN-161 (trifluoroacetate salt)

别名:

Ac-PHSCN-NH2|PHSCN Peptide

产品描述:

ATN-161 is a peptide derived from fibronectin and an integrin αVβ3 and αVβ5 antagonist.{65023} It binds to αVβ3 and αVβ5 receptors (Kds = 0.69 and 1 µM, respectively) in MDA-MB-231 breast cancer cells, as well as inhibits the interaction between αVβ5 and human angiotensin-converting enzyme 2 (ACE2) or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein in a concentration-dependent manner in cell-free assays.{65023,65024} ATN-161 reduces viral titers in Vero E6 cells infected with SARS-CoV-2 (EC50 = 3.16 µM).{65024} It inhibits VEGF-induced migration and capillary tube formation of primary human choroidal endothelial cells when used at a concentration of 0.1 µM.{65025} ATN-161 (1 mg/kg) reduces tumor growth and metastasis in an MDA-MB-231 mouse xenograft model and infarct volume and edema in a mouse model of ischemic stroke induced by middle cerebral artery occlusion (MCAO).{65023,65026}

保存温度:

-20

运输温度:

-20

预期分子量:

711.7

产品形式:

A crystalline solid

有效期:

1460

纯度:

≥95%