Apelin-12 (human, mouse, rat, bovine) (acetate)-其他肽-ELISA_抗体_蛋白_核苷酸

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Apelin-12 (human, mouse, rat, bovine) (acetate)

品牌：Cayman

官网链接

说明书

折扣/货期

货号：36888-1 mg	规格：1 mg	目录价：￥1036
货号：36888-10 mg	规格：10 mg	目录价：￥8176
货号：36888-25 mg	规格：25 mg	目录价：￥17892
货号：36888-5 mg	规格：5 mg	目录价：￥4620

产品详情

产品名称:

Apelin-12 (human, mouse, rat, bovine) (acetate)

别名:

RPRLSHKGPMPF

产品描述:

Apelin-12 is a 12-amino acid peptide fragment corresponding to residues 66-77 of apelin and an endogenous agonist of the apelin receptor (APJ), with roles in viral immunity, digestion, cell cycle regulation, and vasodilation.{69069} It induces calcium mobilization in APJ-Gαq16 cells expressing human APJ (EC50 = 0.18 nM). Apelin-12 inhibits HIV-1 and HIV-2 infection in NP-2/CD4/APJ cells (mean IC50 = 63 µg/ml).{18226} It inhibits or stimulates the expression of genes associated with apoptosis, mitosis, and DNA repair in IEC-6 and Caco-2 cells, respectively, when used at a concentration of 0.01 µM.{69070} Apelin-12 (100-1,000 nM) induces the production of nitric oxide (NO) via PI3K and Akt signaling pathways in human umbilical vein endothelial cells (HUVECs).{69071} In vivo, apelin-12 (20-100 µg/kg) increases gastric acid secretion, as well as stomach histamine synthesis and secretion, in rats.{69072} It also reduces mean arterial pressure (MAP) in rats when administered at a dose of 15 µg/kg.{69073}

保存温度:

-20

运输温度:

-20

预期分子量:

1422.7

产品形式:

A solid

有效期:

1460

纯度:

≥95%