货号:28210 | 规格:100 µg | 目录价:¥4769 |
产品详情
产品名称:
Anthrax Edema Factor (EF) (recombinant from Bacillus anthracis)
产品描述:
Anthrax edema factor (EF) is a component of edema toxin (EdTx) produced by B. anthracis.{50361,50362} It is comprised of an N-terminal protective antigen (PA) binding domain (PABD), an adenylyl cyclase domain, and a helical domain.{50362} Inactive EF binds oligomerized B. anthracis PA on the host cell surface. EF and PA, together known as EdTx, are endocytosed by the host cell, after which PA facilitates translocations of EF into the host cell cytoplasm. There, calmodulin binds the EF helical domain and activates its adenylyl cyclase activity, leading to an increase in intracellular cAMP.
保存温度:
4
运输温度:
4
产品形式:
Each vial, when reconstituted with 100 µl in water, contains 0.1 mg of edema factor from Bacillus anthracis in 5 mM HEPES, 50 mM NaCl, pH 7.5
有效期:
730
纯度:
≥95% (estimated by SDS-PAGE)
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