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2',3'-Dideoxyadenosine-5'-O-triphosphate (sodium salt)
品牌:Cayman
货号:38373 规格:2.4 mg 目录价:¥2842
产品详情
产品名称:
2',3'-Dideoxyadenosine-5'-O-triphosphate (sodium salt)
别名:
ddATP|Dideoxyadenosine-5'-triphosphate
产品描述:
2',3'-Dideoxyadenosine-5'-O-triphosphate is a reverse transcriptase inhibitor (Kis = 20 and 37 nM for the HIV and visna virus enzymes, respectively) and an active metabolite of 2′,3′-dideoxyadenosine (ddA; Item No. 36662) and didanosine (ddI; Item No. 23715).{28262,28268,64902} It is formed from ddI via a 2',3'-dideoxyAMP intermediate by phosphoribosyl pyrophosphate synthase (PRS).{64902} It inhibits DNA polymerase isolated from mouse Ehrlich ascites tumor cells in the presence of ATP or GDP (Kis = 60 and 18 µM, respectively).{28263} 2',3'-Dideoxyadenosine-5'-O-triphosphate and other dideoxynucleoside 5'-triphosphates are commonly used to terminate chain extension by Taq polymerases in PCR assays.{28266}
保存温度:
-80
运输温度:
-80
预期分子量:
563.1
产品形式:
A solution in water
有效期:
730
纯度:
≥95%
CAS号:
99827-72-2
分子式:
C10H12N5O11P3 • 4Na
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