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折扣/货期| 货号：10010132-1 mg | 规格：1 mg | 目录价：￥5320 |
| 货号：10010132-100 µg | 规格：100 µg | 目录价：￥686 |
| 货号：10010132-500 µg | 规格：500 µg | 目录价：￥3024 |
产品详情
产品名称:
15-deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester
别名:
15-deoxy-Δ12,14-PGJ2-2-glyceryl ester
产品描述:
15-deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester (15-deoxy-Δ12,14-PGJ2-2-glyceryl ester) is formed from PGD2 by the elimination of two molecules of water. It binds selectively to PPARγ with an EC50 value of 2 µM in a murine chimera system.{1428,1424} 15-deoxy-Δ12,14-PGJ2-2-glyceryl ester is more potent than PGD2, Δ12-PGJ2, and PGJ2 in stimulating lipogenesis in C3H10T1/2 cells. The EC50 value for induction of adipocyte differentiation in cultured fibroblasts is 7 µM.{1428} PG glycerol esters are generated by the action of cyclooxygenase-2 on the endocannabinoid 2-arachidonyl glycerol.{11045} The biosesynthesis of PGH, PGD, PGE, PGF, and TXA-2-glyceryl ester compounds have all been documented. While the stability and metabolism of these PG products has been investigated,{10555} little is known about their intrinsic biological activity.
保存温度:
-80
运输温度:
-80
预期分子量:
390.5
产品形式:
A solution in ethanol
有效期:
730
纯度:
≥98% (isomer mixture)
分子式:
C23H34O5
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